The article presents the evolution of the approach to humanitarian intervention that in the 21st century had been framed in the concept of Responsibility to Protect. The article focuses particularly on the possibility of adopting R2P rule in Africa, especially second and third pillar of this mechanism Various cases of conflict in Africa and other types of security threats are discussed herein; those which were actually implemented and situations where they were had to be foregone. This description serves the purpose of defining situations when the R2P mechanism is found useful in continental security measures as well as indicating the factors needed to implement it in practice, regardless of pure declarations from regional states and organizations.