The article examines the role of major Latin American regional organizations in promotion of commercial and investment arbitration (through regional international law) as a method of dispute resolution in the region. It also analyses whether there is a relationship between the development of regional law in the field in question and better integration of Latin American economies. Before moving on to the main analysis, the author discusses the phenomenon of regional economic integration in Latin America and considers the role that arbitration plays (or is believed to play) in the processes of liberalization of international trade and investment. The author concludes that it is rather unclear whether the regional initiatives on international arbitration in Latin America have a positive impact on economic integration and development of Latin American countries. Having found that the positive role of the discussed regional initiatives is somewhat ambiguous, the author submits that they neither hamper the economic integration processes in the region nor jeopardize the harmonization efforts in the area of international arbitration undertaken at the global level.